Neurogenic shock is shock Circulatory shock, commonly known simply as shock, is a serious, life-threatening medical condition characterized by a decrease in tissue perfusion to a point at which it is inadequate to meet cellular metabolic needs. As the blood carries oxygen and nutrients around the body, reduced flow hinders the delivery of these components to the tissues, caused by the sudden loss of the autonomic nervous system The autonomic nervous system is the part of the peripheral nervous system that acts as a control system functioning largely below the level of consciousness, and controls visceral functions. The ANS affects heart rate, digestion, respiration rate, salivation, perspiration, diameter of the pupils, micturition (urination), and sexual arousal signals to the smooth muscle Smooth muscle is an involuntary non-striated muscle. It is divided into two sub-groups; the single-unit and multiunit smooth muscle. Within single-unit smooth muscle tissues, the autonomic nervous system innervates a single cell within a sheet or bundle and the action potential is propagated by gap junctions to neighboring cells such that the in vessel The blood vessels are the part of the circulatory system that transport blood throughout the body. There are three major types of blood vessels: the arteries, which carry the blood away from the heart; the capillaries, which enable the actual exchange of water and chemicals between the blood and the tissues; and the veins, which carry blood from walls. This can result from severe central nervous system The central nervous system is the part of the nervous system that coordinates the activity of all parts of the bodies of bilaterian animals—that is, all multicellular animals except sponges and radially symmetric animals such as jellyfish. It contains the majority of the nervous system and consists of the brain and the spinal cord, as well as (brain The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary and spinal cord The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the brain . The brain and spinal cord together make up the central nervous system. The spinal cord extends down to the space between the first and second lumbar vertebrae; it does not extend the entire length of the vertebral column. It is around 4) damage. With the sudden loss of background sympathetic The sympathetic nervous system is one of the three parts of the autonomic nervous system, along with the enteric and parasympathetic systems. Its general action is to mobilize the body's resources under stress; to induce the flight-or-fight response. It is, however, constantly active at a basal level in order to maintain homeostasis stimulation, the vessels suddenly relax resulting in a sudden decrease in peripheral vascular resistance (vasodilation Vasodilation refers to the widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls, particularly in the large arteries, smaller arterioles and large veins. The process is essentially the opposite of vasoconstriction, or the narrowing of blood vessels. When vessels dilate, the flow of blood is increased)[1] and decreased blood pressure In physiology and medicine, hypotension is abnormally low blood pressure. This is best understood as a physiologic state, rather than a disease. It is often associated with shock, though not necessarily indicative of it. Hypotension is the opposite of hypertension, which is high blood pressure. Blood pressure is the force of blood pushing against.
Signs and symptoms
- hypotension In physiology and medicine, hypotension is abnormally low blood pressure. This is best understood as a physiologic state, rather than a disease. It is often associated with shock, though not necessarily indicative of it. Hypotension is the opposite of hypertension, which is high blood pressure. Blood pressure is the force of blood pushing against
- bradycardia Bradycardia , as applied to adult medicine, is defined as a resting heart rate of under 60 beats per minute, though it is seldom symptomatic until the rate drops below 50 beat/min. It may cause cardiac arrest in some patients, because those with bradycardia may not be pumping enough oxygen to their heart. It sometimes results in fainting,
- warm, dry extremities A limb is a jointed, or prehensile (as octopus tentacles or new world monkey tails), appendage of the human or other animal body
- peripheral vasodilation Vasodilation refers to the widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls, particularly in the large arteries, smaller arterioles and large veins. The process is essentially the opposite of vasoconstriction, or the narrowing of blood vessels. When vessels dilate, the flow of blood is increased
- venous pooling
- Poikilothermia
- Priapism Due to PNS stimulation
- decreased cardiac output Cardiac output is the volume of blood being pumped by the heart, in particular by a Left or Right ventricle in the Time interval of one minute. CO may be measured in many ways, for example dm3/min (1 dm3 equals 1000 cm3 or 1 litre). Q is furthermore the combined sum of output from the right ventricle and the output from the left ventricle during (with cervical The neck is the part of the body, on many terrestrial or secondarily aquatic vertebrates that distinguishes the head from the torso or trunk. The Latin term signifying "of the neck" is cervical or high thoracic In human anatomy, the vertebral column is a column usually consisting of 33 vertebrae, the sacrum, intervertebral discs, and the coccyx situated in the dorsal aspect of the torso, separated by spinal discs. It houses and protects the spinal cord in its spinal canal injury)
Treatment of Neurogenic shock
- Large volumes of fluid may be needed to restore normal hemodynamics
- Dopamine (Intropin) is often used either alone or in combination with other inotropic agents.
- Vasopressors (Ephedrine, Norepinephrine, Phenylephrine)
- Atropine Atropine is a tropane alkaloid extracted from deadly nightshade , jimsonweed (Datura stramonium), mandrake (Mandragora officinarum) and other plants of the family Solanaceae. It is a secondary metabolite of these plants and serves as a drug with a wide variety of effects. It is a competitive antagonist for the muscarinic acetylcholine receptor. It (speeds up heart rate and Cardiac Output)
References
- ^ "Dorlands Medical Dictionary:neurogenic shock". http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/seven/000096569.htm.
Categories: Neurology
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